The structures of two archaeal type IV pili illuminate evolutionary relationships

Fengbin Wang; Diana P. Baquero; Zhangli Su; Leticia C. Beltran; David Prangishvili; Mart Krupovic; Edward H. Egelman

doi:10.1038/s41467-020-17268-4

Nature Communications (Jul 2020)

The structures of two archaeal type IV pili illuminate evolutionary relationships

Fengbin Wang,
Diana P. Baquero,
Zhangli Su,
Leticia C. Beltran,
David Prangishvili,
Mart Krupovic,
Edward H. Egelman

Affiliations

Fengbin Wang: Department of Biochemistry and Molecular Genetics, University of Virginia
Diana P. Baquero: Archaeal Virology Unit, Department of Microbiology Institut Pasteur
Zhangli Su: Department of Biochemistry and Molecular Genetics, University of Virginia
Leticia C. Beltran: Department of Biochemistry and Molecular Genetics, University of Virginia
David Prangishvili: Archaeal Virology Unit, Department of Microbiology Institut Pasteur
Mart Krupovic: Archaeal Virology Unit, Department of Microbiology Institut Pasteur
Edward H. Egelman: Department of Biochemistry and Molecular Genetics, University of Virginia

DOI: https://doi.org/10.1038/s41467-020-17268-4
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 10

Abstract

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Archaeal type IV pili (T4P) mediate adhesion to surfaces and are receptors for hyperthermophilic archaeal viruses. Here, the authors present the cryo-EM structures of two archaeal T4P from Pyrobaculum arsenaticum and Saccharolobus solfataricus and discuss evolutionary relationships between bacterial T4P, archaeal T4P and archaeal flagellar filaments.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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