Effect of perioperative levosimendan administration on postoperative N-terminal pro-B-type natriuretic peptide concentration in patients with increased cardiovascular risk factors undergoing non-cardiac surgery: protocol for the double-blind, randomised, placebo-controlled IMPROVE trial

• Sascha Treskatsch,
• Alexandra Graf,
• Edith Fleischmann,
• Christian Reiterer,
• Barbara Kabon,
• Alexander Taschner,
• Nikolas Adamowitsch,
• Melanie Fraunschiel,
• Katharina Horvath,
• Melanie Kuhrn,
• Theresa Clement,
• Christian Berger

Affiliations

Sascha Treskatsch

Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany

Alexandra Graf

Center for Medical Statistics, Informatics and Intelligent Systems, Medical University of Vienna, Wien, Austria

Edith Fleischmann

Department of Anesthesia, Intensive Care Medicine and Pain Medicine, Outcome Research Consortium, Cleveland, Ohio, USA

Christian Reiterer

Department of Anesthesia, Intensive Care Medicine and Pain Medicine, Outcome Research Consortium, Cleveland, Ohio, USA

Barbara Kabon

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Alexander Taschner

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Nikolas Adamowitsch

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Melanie Fraunschiel

ITSC - IT Systems & Communications, Medical University of Vienna, Wien, Austria

Katharina Horvath

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Melanie Kuhrn

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Theresa Clement

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Wien, Austria

Christian Berger

Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany