Geographic Range Expansion for Rat Lungworm in North America

Abstract

Using quantitative PCR analysis and DNA sequencing, we provide evidence for the presence of rat lungworm (Angiostrongylus cantonensis) in Oklahoma, USA, and identified a potentially novel rat host (Sigmodon hispidus). Our results indicate a geographic range expansion for this medically and ecologically relevant parasite in North America.

Keywords

• real-time PCR
• quantitative PCR
• Sigmodon hispidus
• zoonoses
• emerging infectious diseases
• rat lungworm