First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016

C. Pichler; M. Büchsel; J.W. Rossen; M. Vavra; S. Reuter; W.V. Kern; R. Thimme; A. Mischnik

doi:10.1016/j.nmni.2017.02.006

New Microbes and New Infections (May 2017)

First report of invasive liver abscess syndrome with endophthalmitis caused by a K2 serotype ST2398 hypervirulent Klebsiella pneumoniae in Germany, 2016

C. Pichler,
M. Büchsel,
J.W. Rossen,
M. Vavra,
S. Reuter,
W.V. Kern,
R. Thimme,
A. Mischnik

Affiliations

C. Pichler: Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
M. Büchsel: Institute for Medical Microbiology and Hygiene, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
J.W. Rossen: Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
M. Vavra: Division of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
S. Reuter: Department of Infection Prevention and Hospital Hygiene, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
W.V. Kern: Division of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
R. Thimme: Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany
A. Mischnik: Division of Infectious Diseases, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany

DOI: https://doi.org/10.1016/j.nmni.2017.02.006
Journal volume & issue: Vol. 17, no. C
pp. 77 – 80

Abstract

Read online

We report a case of severe infection with liver abscess and endophthalmitis caused by a hypervirulent Klebsiella pneumoniae strain in an immunocompetent German male patient without travel history to Asia. Phenotypic and molecular characterization showed high similarity to the reference genome NTUH-K2044 isolated in Asia. The isolate was assigned as ST2398 (clonal complex 66). The findings underline global spread of hypervirulent Klebsiella pneumoniae strains to Europe.

Published in New Microbes and New Infections

ISSN: 2052-2975 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://www.sciencedirect.com/journal/new-microbes-and-new-infections

About the journal

Abstract

Keywords