Communications Biology (May 2022)
Cytosolic peptides encoding CaV1 C-termini downregulate the calcium channel activity-neuritogenesis coupling
- Yaxiong Yang,
- Zhen Yu,
- Jinli Geng,
- Min Liu,
- Nan Liu,
- Ping Li,
- Weili Hong,
- Shuhua Yue,
- He Jiang,
- Haiyan Ge,
- Feng Qian,
- Wei Xiong,
- Ping Wang,
- Sen Song,
- Xiaomei Li,
- Yubo Fan,
- Xiaodong Liu
Affiliations
- Yaxiong Yang
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Zhen Yu
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Jinli Geng
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Min Liu
- School of Medicine, Tsinghua University
- Nan Liu
- Center for Life Sciences, School of Life Sciences, Yunnan University
- Ping Li
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Weili Hong
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Shuhua Yue
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- He Jiang
- School of Medicine, Tsinghua University
- Haiyan Ge
- School of Medicine, Tsinghua University
- Feng Qian
- School of Pharmaceutical Sciences, Tsinghua University
- Wei Xiong
- School of Life Sciences, Tsinghua University
- Ping Wang
- Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University
- Sen Song
- School of Medicine, Tsinghua University
- Xiaomei Li
- School of Medicine, Tsinghua University
- Yubo Fan
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- Xiaodong Liu
- Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University
- DOI
- https://doi.org/10.1038/s42003-022-03438-1
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 18
Abstract
When present in the cytosol, a variety of peptides encoded by the distal carboxyl-termini of the L-type CaV1 calcium channels downregulate channel activity and neurite outgrowth.
