FROM SKIN INFECTIONS TO BARIATRIC SURGERY IN PATIENTS WITH ENDOCRINE TUMOURS

Abstract

Obesity is associated with multiple complications like cardiovascular, oncologic, including skin infections potentially with a more severe evolution than in subjects with normal weight. We aim is to introduce two cases of females who initially presented with skin infections associating obesity and two different types of endocrine tumours; both of them underwent bariatric surgery. One case of a young female who had acne and menses anomalies was confirmed with macroprolactinoma and treated with cabergoline with menses control. For obesity she had bariatric surgery with weight and acne control but associating long term hypovitaminosis D. The second case is a menopausal woman with metabolic syndrome and different persistent skin infections in association with features of cardio-metabolic anomalies which were confirmed as adrenal Cushing’s syndrome and referred for unilateral adrenalectomy. The improvement of mentioned parameters was not associated with obesity control so bariatric surgery was done. She suffered a shoulder fracture and she was confirmed with osteoporosis (a lumbar T-score of -3.3 SD). The values of 25-hydroxyvitamin D remained normal only under oral replacement with vitamin D supplements and zolendronic acid was added. Obesity underlines heterogeneous aspects including dermatological, metabolic, cardiovascular and endocrine conditions; some of them are dramatically improved after bariatric surgery, yet not hipovitaminosis D and osteoporosis especially in menopausal women. The prolactin excess, Cushing’s disease or just obesity itself may cause repeated skin infections or acne.

Keywords

• skin
• acne
• bariatric surgery