Memorias do Instituto Oswaldo Cruz (Sep 1997)

Update of the Gene Discovery Program in Schistosoma mansoni with the Expressed Sequence Tag Approach

  • Élida ML Rabelo,
  • Glória R Franco,
  • Vasco AC Azevedo,
  • Heloisa B Pena,
  • Túlio M Santos,
  • Wendell SF Meira,
  • Neuza A Rodrigues,
  • José Miguel Ortega,
  • Sérgio DJ Pena

DOI
https://doi.org/10.1590/S0074-02761997000500012
Journal volume & issue
Vol. 92, no. 5
p. 625

Abstract

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Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been described in S. mansoni. Among the newly discovered genes there are several of significant biological interest such as synaptophysin, NIFs-like and rho-GDP dissociation inhibitor

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