“Corneal Nerves, CD11c+ Dendritic Cells and Their Impact on Ocular Immune Privilege”

Abstract

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The eye and the brain have limited capacities for regeneration and as such, immune-mediated inflammation can produce devastating consequences in the form of neurodegenerative diseases of the central nervous system or blindness as a result of ocular inflammatory diseases such as uveitis. Accordingly, both the eye and the brain are designed to limit immune responses and inflammation – a condition known as “immune privilege”. Immune privilege is sustained by physiological, anatomical, and regulatory processes that conspire to restrict both adaptive and innate immune responses.

Keywords

• contrasuppressor cells
• nerves
• dendritic cells
• immune privilege
• cornea