Pheochromocytoma with Negative Metanephrines: A Rarity and the Significance of Dopamine Secreting Tumors

Michael Bozin; Alastair Lamb; Lydia Johns Putra

doi:10.1016/j.eucr.2017.02.002

Urology Case Reports (May 2017)

Pheochromocytoma with Negative Metanephrines: A Rarity and the Significance of Dopamine Secreting Tumors

Michael Bozin,
Alastair Lamb,
Lydia Johns Putra

Affiliations

Michael Bozin: Department of Urology, Ballarat Health Services, Victoria, Australia
Alastair Lamb: Department of Surgical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia
Lydia Johns Putra: Department of Urology, Ballarat Health Services, Victoria, Australia

DOI: https://doi.org/10.1016/j.eucr.2017.02.002
Journal volume & issue: Vol. 12, no. C
pp. 51 – 53

Abstract

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We describe a case of a 25-year-old female with a dopamine secreting PPGL diagnosed retrospectively with biochemical analysis. This finding resulted in change in approach to investigation and management, given their important clinical implications. There are important differences in management of dopamine secreting PPGL compared to classical noradrenaline and adrenaline-secreting PPGL. This includes the risk of peri-operative cardiovascular collapse peri-operatively with alpha/beta blockade, risk of malignancy/recurrence, and associated genetic abnormalities.

Published in Urology Case Reports

ISSN: 2214-4420 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology
Website: http://www.urologycasereports.com/

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