Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prospective skin cancer registry ADOREG

• Dirk Schadendorf,
• Lucie Heinzerling,
• Lisa Zimmer,
• Ralf Gutzmer,
• Alexander Kreuter,
• Andrea Forschner,
• Elisabeth Livingstone,
• Selma Ugurel,
• Alexander Roesch,
• Peter Mohr,
• Thilo Gambichler,
• Patrick Terheyden,
• Sebastian Haferkamp,
• Friedegund Meier,
• Claudia Pfoehler,
• Dirk Debus,
• Rudolf Herbst,
• Frank Meiss,
• Carsten Weishaupt,
• Jochen Utikal,
• Martin Kaatz,
• Jens Ulrich,
• Edgar Dippel,
• Michael Weichenthal,
• Maike Trommer,
• Ulrike Leiter,
• Kerstin Schatton,
• Cindy Franklin,
• Leonie Bluhm,
• Imke Grimmelmann,
• Marlene Garzarolli,
• Dorothee Nashan,
• Michael Sachse,
• Julia Welzel,
• Gerhard Weyandt,
• Eren Celik,
• Iris Helfrich,
• Susanne Horn

Affiliations

Dirk Schadendorf

Department of Dermatology, University Hospital of Essen, Essen, Germany

Lucie Heinzerling

Department of Dermatology-Oncology, University Hospital München, München, Germany

Lisa Zimmer

Department of Dermatology, University Hospital of Essen, Essen, Germany

Ralf Gutzmer

Department of Dermatology, Skin Cancer Center Minden, Minden, Germany

Alexander Kreuter

Department of Dermatology, Venereology and Allergology, Helios St Elisabeth Hospital Oberhausen, University Witten-Herdecke, Oberhausen, Germany

Andrea Forschner

Department of Dermatology, University Hospital Tuebingen, Tuebingen, Germany

Elisabeth Livingstone

Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Selma Ugurel

Department of Dermatology, University Hospital of Essen, Essen, Germany

Alexander Roesch

Aff1 0000 0001 0262 7331grid.410718.bDepartment of DermatologyUniversity Hospital Essen Essen Germany

Peter Mohr

Department of Dermatology, Elbe Kliniken Buxtehude, Buxtehude, Germany

Thilo Gambichler

Department of Dermatology, Ruhr University Bochum, Bochum, Germany

Patrick Terheyden

Department of Dermatology, University Hospital of Lübeck, Lübeck, Germany

Sebastian Haferkamp

Department of Dermatology, University Hospital Regensburg, Regensburg, Germany

Friedegund Meier

Skin Cancer Center at the University Cancer Centre and National Center for Tumor Diseases Dresden; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany

Claudia Pfoehler

Department of Dermatology, Saarland University Medical Center, Homburg, Germany

Dirk Debus

Skin Cancer Center, Department of Dermatology, Paracelsus Medical University, General Hospital Nuremberg, Nuremberg, Germany

Rudolf Herbst

Department of Dermatology, HELIOS Klinikum Erfurt, Erfurt, Germany

Frank Meiss

Skin Cancer Center, Department of Dermatology and Venerology, Medical Centre University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Carsten Weishaupt

Department of Dermatology, University Hospital of Münster, Münster, Germany

Jochen Utikal

2Heidelberg University, Mannheim, Germany

Martin Kaatz

Department of Dermatology, SRH Wald-Klinikum Gera, Gera, Germany

Jens Ulrich

Department of Dermatology and Skin Cancer Center, Harzklinikum Dorothea Christiane Erxleben, Quedlinburg, Germany

Edgar Dippel

Department of Dermatology, Ludwigshafen Medical Center, Ludwigshafen, Germany

Michael Weichenthal

Department of Dermatology, University Hospital Schleswig-Holstein - Campus Kiel, Kiel, Germany

Maike Trommer

4 Department of Radiation Oncology, CyberKnife and Radiotherapy, University Hospital Cologne, Cologne, Germany

Ulrike Leiter

Department of Dermatology, University Hospital of Tübingen, Tübingen, Germany

Kerstin Schatton

Department of Dermatology, Heinrich Heine University Medical Faculty, Düsseldorf, Germany

Cindy Franklin

Department of Dermatology, University Hospital Cologne, Cologne, Germany

Leonie Bluhm

Department of Dermatology, Elbe Kliniken Buxtehude, Buxtehude, Germany

Imke Grimmelmann

Department of Dermatology, Hannover Medical School, Hannover, Germany

Marlene Garzarolli

Skin Cancer Center at the University Cancer Centre Dresden and National Center for Tumor Diseases, Dresden, Germany; Department of Dermatology, University Hospital Carl Gustav Carus, Dresden, Germany

Dorothee Nashan

Department of Dermatology, Hospital of Dortmund, Dortmund, Germany

Michael Sachse

Department of Dermatology, Klinikum Bremerhaven Reinkenheide, Bremerhaven, Germany

Julia Welzel

Department of Dermatology and Allergology, University Hospital Augsburg, Augsburg, Germany

Gerhard Weyandt

Department of Dermatology and Allergology, Hospital Bayreuth, Bayreuth, Germany

Eren Celik

Department of Radiation Oncology and Cyberknife Center, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany

Iris Helfrich

Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany and German Cancer Consortium (DKTK) partner site Essen/Düsseldorf, Essen, Germany

Susanne Horn

Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany and German Cancer Consortium (DKTK) partner site Essen/Düsseldorf, Essen, Germany