Nature Communications (Jun 2016)

Circadian regulation of human cortical excitability

  • Julien Q. M. Ly,
  • Giulia Gaggioni,
  • Sarah L. Chellappa,
  • Soterios Papachilleos,
  • Alexandre Brzozowski,
  • Chloé Borsu,
  • Mario Rosanova,
  • Simone Sarasso,
  • Benita Middleton,
  • André Luxen,
  • Simon N. Archer,
  • Christophe Phillips,
  • Derk-Jan Dijk,
  • Pierre Maquet,
  • Marcello Massimini,
  • Gilles Vandewalle

DOI
https://doi.org/10.1038/ncomms11828
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 10

Abstract

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Cognitive performance is impaired after prolonged wakefulness, yet the contribution of circadian rhythms for proper brain function remains unclear. Here the authors show that cortical excitability measured using TMS exhibits robust circadian dynamics which is correlated with cognitive performance.