Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus

Jelena Veličković; Jelena Veličković; Tatjana Adžić Vukičević; Tatjana Adžić Vukičević; Aleksandra Radovanović Spurnić; Aleksandra Radovanović Spurnić; Igor Lazić; Bojana Popović; Bojana Popović; Ivan Bogdanović; Ivan Bogdanović; Savo Raičević; Dragana Marić; Dragana Marić; Ivana Berisavac; Ivana Berisavac

doi:10.3389/fmed.2022.973817

Frontiers in Medicine (Aug 2022)

Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus

Jelena Veličković,
Jelena Veličković,
Tatjana Adžić Vukičević,
Tatjana Adžić Vukičević,
Aleksandra Radovanović Spurnić,
Aleksandra Radovanović Spurnić,
Igor Lazić,
Bojana Popović,
Bojana Popović,
Ivan Bogdanović,
Ivan Bogdanović,
Savo Raičević,
Dragana Marić,
Dragana Marić,
Ivana Berisavac,
Ivana Berisavac

Affiliations

Jelena Veličković: COVID Hospital Batajnica, University Clinical Center of Serbia, Belgrade, Serbia
Jelena Veličković: School of Medicine, University of Belgrade, Belgrade, Serbia
Tatjana Adžić Vukičević: COVID Hospital Batajnica, University Clinical Center of Serbia, Belgrade, Serbia
Tatjana Adžić Vukičević: School of Medicine, University of Belgrade, Belgrade, Serbia
Aleksandra Radovanović Spurnić: COVID Hospital Batajnica, University Clinical Center of Serbia, Belgrade, Serbia
Aleksandra Radovanović Spurnić: School of Medicine, University of Belgrade, Belgrade, Serbia
Igor Lazić: Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
Bojana Popović: COVID Hospital Batajnica, University Clinical Center of Serbia, Belgrade, Serbia
Bojana Popović: School of Medicine, University of Belgrade, Belgrade, Serbia
Ivan Bogdanović: School of Medicine, University of Belgrade, Belgrade, Serbia
Ivan Bogdanović: Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
Savo Raičević: Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
Dragana Marić: School of Medicine, University of Belgrade, Belgrade, Serbia
Dragana Marić: Clinic for Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia
Ivana Berisavac: School of Medicine, University of Belgrade, Belgrade, Serbia
Ivana Berisavac: Clinic for Neurology, University Clinical Center of Serbia, Belgrade, Serbia

DOI: https://doi.org/10.3389/fmed.2022.973817
Journal volume & issue: Vol. 9

Abstract

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Coronavirus disease (COVID-19) in immunocompromised patients represents a major challenge for diagnostics, surveillance, and treatment. Some individuals remain SARS-CoV-2 PCR-positive for a prolonged period. The clinical and epidemiological significance of this phenomenon is not well understood. We report a case of a patient with a history of systemic lupus erythematosus (SLE) who has been persistently SARS-CoV-2 PCR positive for 9 months, with multiple thromboembolic complications, and development of nocardial brain abscess successfully treated with surgery and antibiotics.

Published in Frontiers in Medicine

ISSN: 2296-858X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.frontiersin.org/journals/medicine

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