The Demographic, Clinical and Laboratory Characteristics of Patients with Allergic and Non-allergic Asthma in Van Province

Abstract

INTRODUCTION: Asthma is a prevalent disease that can cause different clinical features due to various underlying mechanisms. Detecting different types of asthma is important in disease management. We aimed to compare the features of allergic and non-allergic patients and to assess the clinical characteristics of patients with asthma in ***. METHODS: We included 302 adult patients with asthma with compatible history, physical examination and pulmonary function tests. We evaluated the demographic features and allergy test results in addition to clinical and laboratory findings on patients with asthma. The characteristics of the patients allocated into two groups with allergic and non-allergic, asthma were compared. RESULTS: Among the patients, 80% were women and the median age was 35 years. Allergy tests indicated that the most frequently observed inhalant agents were pollens (59%), followed by house dusts (55%), molds (6%) and animal epitheliums (3%). More than half (57%) of the patients exhibited allergic asthma. Non-allergic asthma was correlated with longer disease duration and more severe disease while the presence of a family history of an allergic disease was higher in patients with allergic asthma (p=0,001, p=0,001 and p=0,001, respectively). Total IgE levels were significantly higher in allergic asthma, although there was no significant difference concerning eosinophil counts (p=0,001 and p=0,936, respectively). DISCUSSION AND CONCLUSION: This study demonstrated that the majority of patients with asthma were allergic in ***, with pollen allergy being the most common. These findings can aid doctors in distinguishing asthma phenotypes. As a result, more successful treatments will be provided in managing patients with asthma.

Keywords

• asthma
• allergic asthma
• non-allergic asthma
• allergy test
• allergen sensitization