Nature Communications (Jul 2019)

RNA structure drives interaction with proteins

  • Natalia Sanchez de Groot,
  • Alexandros Armaos,
  • Ricardo Graña-Montes,
  • Marion Alriquet,
  • Giulia Calloni,
  • R. Martin Vabulas,
  • Gian Gaetano Tartaglia

DOI
https://doi.org/10.1038/s41467-019-10923-5
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Interactions between protein and RNA occur on a large scale, and are often studied from a proteincentric point of view. Here the authors show that the number and strength of RNA-protein interactions correlate with the amount of RNA structure, which impacts the biological activity of the transcript.