Frontiers in Plant Science (Jan 2023)

The role of corepressor HOS15-mediated epigenetic regulation of flowering

  • Li-Jun Huang,
  • Yukun Wang,
  • Zeng Lin,
  • Dong Jiang,
  • Yong Luo,
  • Ning Li,
  • Ning Li

DOI
https://doi.org/10.3389/fpls.2022.1101912
Journal volume & issue
Vol. 13

Abstract

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Regulation of gene expression underpins gene function and is essential for regulation of physiological roles. Epigenetic modifications regulate gene transcription by physically facilitating relaxation or condensation of target loci in chromatin. Transcriptional corepressors are involved in chromatin remodeling and regulate gene expression by establishing repressive complexes. Genetic and biochemical studies reveal that a member of the Groucho/Thymidine uptake 1 (Gro/Tup1) corepressor family, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 15 (HOS15), is recruited via the evening complex (EC) to the GIGANTEA (GI) promoter to repress gene expression, and modulating flowering time. Therefore, HOS15 connects photoperiodic pathway and epigenetic mechanism to control flowering time in plants. In addition, growing body of evidence support a diverse roles of the epigenetic regulator HOS15 in fine-tuning plant development and growth by integrating intrinsic genetic components and various environmental signals.

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