Transition Metal Catalysis for Pharmaceutical Intermediates and APIs

Abstract

Rohner AG, a medium-sized Swiss company, has moved from toll manufacturing of building blocks and starting materials to the custom manufacturing of intermediates and APIs for the life science industry. Therefore, Rohner AG has expanded its technology portfolio to new technologies such as transition metal catalysis. Examples for asymmetric hydrogenation, Suzuki coupling and carbonylation are provided. In addition, the necessary changes in equipment and project management are presented and discussed.

Keywords

• Asymmetric hydrogenation
• Carbonylation
• Custom synthesis
• Suzuki coupling