Radiology Case Reports (Aug 2019)
Posterior reversible encephalopathy syndrome and Wernicke encephalopathy in patient with acute graft-versus-host disease
Abstract
Graft-versus-host disease (GVHD) is an immune triggered process leading to severe immune dysregulation and organ dysfunction until death and it is one of the worst medical complications after a transplant. Patients with GVHD may have several neurological alterations: during this acute severe phase there is coexistence of various and nonspecific neurological symptoms. We are reporting a case of a 53 year old woman with severe GVHD after bone marrow transplant with acute neurological signs and symptoms. MRI study showed findings consistent with Posterior reversible encephalopathy syndrome and Wernicke encephalopathy. Keywords: Acute graft-versus-host disease, Posterior reversible encephalopathy syndrome, Wernicke encephalopathy, Magnetic resonance imaging