Ambulatory blood pressure monitoring and chronotherapy response in a diabetic hypertensive population

Abstract

Background: multiples studies support the use of ambulatory blood pressure monitoring, the follow up procedure and evaluation of the diabetic patient with hypertension; it is considered a golden rule in the control of these sick people and predict target organ. Objective: to characterize the diabetic hypertensive patients by means of the monitoring parameters of blood pressure (circadian rhythm, pulse pressure, hypertensive charge, hypertension at wake up time, body mass index, and the response to chronotherapy) Methods: an descriptive longitudinal study was conducted in order to characterize the diabetic hypertensive patients by means of a 24 hour blood pressure ambulatory monitoring and its response to the chronotherapy, at Manuel Ascunce Domenech Universitary Hospital laboratory from 2017 to 2018. The target universe was composed of 179 cases with criteria of high blood pressure and diabetes diagnostics associated for over 12 months, accounting 70 % of the blood pressure valid measurements in 24 hours. Results: in the research, the female gender prevailed; over 60 years the comorbidity increased (obesity, left ventricular hypertrophy, kidney disease and chronic ischemic cardiopathy). The 50 % of the cases showed no dipper circadian rhythm and the chronotherpy diminished to 10 % the night systolic hypertensive charge and the pulse pressure. Conclusions: the ambulatory blood pressure monitoring proved to be a valuable tool to facilitate accurate information about the 24-hour blood pressure profile, it made possible to individualize the treatment and determine the vascular damage. The response to the chronotherapy facilitated the hypertensive diabetic patient control. DeCS: BLOOD PRESSURE MONITORING, AMBULATORY; DRUG CHRONOTHERAPY; ARTERIAL PRESSURE/drug effects; DIABETES COMPLICATIONS/drug therapy; RISK FACTORS.