Assessment of Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios in Patients with Temporal Lobe Epilepsy

Abstract

Objectives:This retrospective study aims to evaluate preoperative levels of neutrophil to lymphocyte (NLR) and platelet to lymphocyte ratios (PLR) in patients with temporal lobe epilepsy and to compare with controls.Methods:Patients and control groups consisted of 36 and 35 subjects, respectively, and routine complete blood count was obtained for NLR and PLR analysis.Results:The two ratios were higher in patients, but differences were not significant (p>0.05). Disease severity, such as high seizure frequency, duration of seizure, and presence of the history of febrile seizure, was not significantly correlated either with NLR or PLR. Findings did not provide evidence of usefulness for discrimination between temporal lobe epilepsy and controls.Conclusion:Further prospective studies, including a larger sample size, should be conductedto have more valuable results for interpretation.

Keywords

• epilepsy
• inflammation
• neutrophil to lymphocyte ratio
• platelet to lymphocyte ratio
• temporal lobe epilepsy