Neopterin and the Acute Phase Response In Human Immunodeficiency Virus Type 1 (HIV -1) Infection

Zangerle R.; Fuchs D.; Reibnegger G.; Artner-Dworzak E.; Fritsch P.; Wachter H.

doi:10.1515/pteridines.1991.3.3.167

Pteridines (Sep 1991)

Neopterin and the Acute Phase Response In Human Immunodeficiency Virus Type 1 (HIV -1) Infection

Zangerle R.,
Fuchs D.,
Reibnegger G.,
Artner-Dworzak E.,
Fritsch P.,
Wachter H.

Affiliations

Zangerle R.: AIDS Unit, Department of Dermatology and Venereology, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria
Fuchs D.: Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria
Reibnegger G.: Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria
Artner-Dworzak E.: Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria
Fritsch P.: AIDS Unit, Department of Dermatology and Venereology , University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria
Wachter H.: Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria

DOI: https://doi.org/10.1515/pteridines.1991.3.3.167
Journal volume & issue: Vol. 3, no. 3
pp. 167 – 170

Abstract

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Three markers of acute phase response - C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), ferritin - and two markers of immune activation - urinary neopterin, β2-microglobulin - were measured in 60 HIV-l infected individuals; β2microglobulin and ferritin increased mainly in the later stages WR 5 and WR 6 but identical in WR 1 - WR 4. The data indicate that chronic bacterial infections are unlikely to be the cause of immune activation in patients with HIV-l infection.

Published in Pteridines

ISSN: 0933-4807 (Print); 2195-4720 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry: Crystallography
Website: https://www.degruyter.com/view/j/pteridines

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