A Comparative Study of Nomegestrol Acetate and a Combination of Ethinylestradiol and Levonorgestrel for Delaying Menstruation among Umrah Pilgrims

Abstract

Objective: To compare the effectiveness efficacy of nomegestrol acetate with and combination of ethinylestradiol and levonorgestrel as a regimen for delaying menstruation in Umrah pilgrims in Palembang city. Methods: This single-blind randomized controlled trial was conducted in Hajj and Umrah Guidance Group in Palembang city during December 2016 to January 2017. Population of this study was 30 women who meet the inclusion and exclusion criteria. Frequency and distribution of data was described in a table. Effectiveness and the side effects treatment between the two groups were analyzed with Chi Square test. Data was were analyzed using SPSS version 18.0. Results: There were no differences in age, education, occupation, parity, body weight, height and contraceptive history between two both groups (all p values > 0.05). Statistical analysis showed there was no difference in spotting between nomegestrol acetate 5 mg or a combination of levonorgestrel 150 mcg and 30 mcg ethinylestradiol in Umrah pilgrims (p = 1.000). Other side effects such as (dizziness, depression, breast tenderness, heavy limbs, nauseam and vomiting) between the two groups could not be analyzed because all subjects did not experience any other side effects. Conclusion: There is no difference in effectiveness between nomegestrol acetate 5 mg or combination of levonorgestrel 150 mcg and 30 mcg ethinylestradiol as a regimen for delaying menses in Umrah pilgrims in Palembang city. [Indones J Obstet Gynecol 2018; 6-1: 45-49] Keywords: delay menstruation, ethinylestradiol, levonorgestrel, nomegestrol, side effects, spotting, umrah