A study of sleep quality and quality of life in children with atopic dermatitis between 6 and 12 years of age

Abstract

Introduction: Atopic dermatitis (AD) is a common, chronic, relapsing dermatitis, affecting mainly children. It is associated with intense pruritus which can disrupt the sleep and quality of life (QOL), thereby impairing the neurocognitive development. An understanding of the link between severity of AD and sleep quality in children may help in better treatment of this condition. Materials and Methods: A hospital-based cross-sectional study was conducted to correlate severity of AD with sleep quality and QOL. Sixty-six children with AD were enrolled for the study. In addition to basic demographic details, all patients were analyzed for disease severity using SCORing AD (SCORAD) score. The QOL and sleep quality were evaluated using Children's Dermatology Life Quality Index (CDLQI) questionnaire and Children's Sleep Habits Questionnaire (CSHQ), respectively. Results: The mean age of the study group was 8.94 ± 1.94 years and mean body mass index was 19.97 ± 2.69 kg/m2. The median SCORAD score was 32 ± 50. Mean CSHQ score was 43.17 ± 7.15, and it showed a positive correlation with SCORAD score (R2 = 0.655; P = 0.000). Similarly, median score of CDLQI was 14 ± 18, which also showed a positive correlation with SCORAD score (R2 = 0.822; P = 0.000). All the domains of CDLQI questionnaire were affected by the disease. In the CSHQ questionnaire, all parameters were affected except parasomnias and sleep-disordered breathing. Conclusion: The study demonstrated a significant association between severity of AD with sleep quality and QOL. It highlights the need for interventions to diminish sleep problems and to improve QOL in children with AD.

Keywords

• atopic dermatitis
• child
• quality of life
• severity of illness index
• sleep quality