Does post-void residual urine volume affect potential recurrence risk for non-muscle invasive bladder cancer?

Abstract

Aim: Bladder cancer is the second most common urological malignancy after prostate cancer. Increase in the post-void residual (PVR) volume may result in an increase in the risk of cancer recurrence. Methods: Patient demographic data, tumor stage and grade, PVR volume and 2 years follow-up data for recurrence were obtained and evaluated. Results: One-hundred-and-nineteen patients were subdivided into three groups according to PVR urine volume. The increase of PVR volume was related to short recurrence-free survival (RFS) especially for patients with PVR volume of 60 ml or more. Conclusion: Low PVR volume in patients with non-muscle invasive bladder cancer may play a role in reducing cancer recurrence. However further research is needed in this field.

Keywords

• bladder cancer recurrence
• intravesical chemotherapy
• intravesical immunotherapy (BCG)
• non-muscle invasive bladder cancers (NMIBCs)
• post-voiding residual urine volume (PVR)
• trans urethral resection of bladder tumor (TURBT)