Journal of Advanced Research (Jul 2023)

The mortalities of female-specific cancers in China and other countries with distinct socioeconomic statuses: A longitudinal study

  • Dongming Jiang,
  • Zheyun Niu,
  • Xiaojie Tan,
  • Haiwei He,
  • Longbing Ren,
  • Jiaying Shen,
  • Xiaoqiong Zhu,
  • Pei Zhao,
  • Mei Liu,
  • Hongsen Chen,
  • Ruihua Wang,
  • Qi Li,
  • Guangwen Cao

Journal volume & issue
Vol. 49
pp. 127 – 139

Abstract

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Introduction: Female-specific cancers seriously affect physical and psychological health of women worldwide. Objectives: We aimed to elucidate trends in the age-standardized mortality rates (ASMRs) of breast cancer, cervical cancer, uterine cancer, and ovarian cancer in female populations with different socioeconomic statuses in China and in countries with different Human Development Index (HDI). Methods: A longitudinal study was performed using the data of cancer death in China and other 39 countries. The mortality rates were standardized with the Segi’s world population. Trends in the mortalities were exhibited by estimated annual percentage change (EAPC). Pearson correlation was used to assess the association between EAPC and HDI. Results: In mainland China, female breast cancer, cervical cancer, uterine cancer, and ovarian cancer accounted for 6.60 %, 4.21 %, 2.50 %, and 2.02 % of cancer death (n = 1,314,040) in women with 1,220,251,032 person-years, respectively. The ASMRs of cervical cancer (EAPC = 3.87 %, P < 0.001) and ovarian cancer (EAPC = 1.81 %, P < 0.001) increased, that of female breast cancer unchanged, whereas that of uterine cancer was extremely higher and rapidly decreased (EAPC = − 7.65 %, P < 0.001), during 2004–2019. The ASMRs of female breast and ovarian cancers were higher in urban and developed regions than in rural and undeveloped regions, in contrast to cervical and uterine cancers. The ASMRs of female breast and ovarian cancers were lower in China than in other countries, in contrast to uterine cancer. The ASMR of cervical cancer decreased, that of uterine cancer increased, in other countries during 2004–2017. EAPCs for the ASMRs of breast and ovarian cancers were inversely correlated to HDI. Conclusion: The ASMRs of cervical and ovarian cancers increased, in contrast to uterine cancer, in China during socioeconomic transition. Trends in the ASMRs of breast and ovarian cancers were inversely associated with HDI. These data help control female-specific cancers.

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