Fulminant hepatic failure after simultaneous kidney-pancreas transplantation: a case report

Abstract

Abstract We describe an unusual case of hyperacute hepatic failure following general anesthesia in a patient receiving a simultaneous kidney-pancreas transplant. Despite an aggressive evaluation of structural, immunological, viral, and toxicological causes, a definitive cause could not be elucidated. The patient required a liver transplant and suffered a protracted hospital course. We discuss the potential causes of fulminant hepatic failure and the perioperative anesthesia management of her subsequent liver transplantation.

Keywords

• Liver failure
• Kidney-pancreas transplant
• Volatile agents
• Liver transplant
• Drug reaction
• Isoflurane toxicity
• Adverse drug reaction
• Inhalational anesthesia