mBio (Feb 2021)
A Trap-Door Mechanism for Zinc Acquisition by <i>Streptococcus pneumoniae</i> AdcA
- Zhenyao Luo,
- Jacqueline R. Morey,
- Evelyne Deplazes,
- Alina Motygullina,
- Aimee Tan,
- Katherine Ganio,
- Stephanie L. Neville,
- Nikolaos Eleftheriadis,
- Michael Isselstein,
- Victoria G. Pederick,
- James C. Paton,
- Thorben Cordes,
- Jeffrey R. Harmer,
- Bostjan Kobe,
- Christopher A. McDevitt
Affiliations
- Zhenyao Luo
- School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia
- Jacqueline R. Morey
- Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia
- Evelyne Deplazes
- ORCiD
- School of Life Sciences, University of Technology Sydney, Ultimo, New South Wales, Australia
- Alina Motygullina
- Centre for Advanced Imaging, The University of Queensland, St. Lucia, Queensland, Australia
- Aimee Tan
- ORCiD
- Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia
- Katherine Ganio
- ORCiD
- Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia
- Stephanie L. Neville
- ORCiD
- Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia
- Nikolaos Eleftheriadis
- ORCiD
- Molecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands
- Michael Isselstein
- Physical and Synthetic Biology, Faculty of Biology, Ludwig Maximilians-Universität München, Planegg-Martinsried, Germany
- Victoria G. Pederick
- Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia
- James C. Paton
- ORCiD
- Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia
- Thorben Cordes
- ORCiD
- Molecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands
- Jeffrey R. Harmer
- School of Pharmacy and Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia
- Bostjan Kobe
- ORCiD
- School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia
- Christopher A. McDevitt
- ORCiD
- Department of Molecular and Biomedical Science, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia
- DOI
- https://doi.org/10.1128/mBio.01958-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
Zinc is an essential nutrient for the virulence of bacterial pathogens such as Streptococcus pneumoniae