HIV infection in patients of advanced age: clinical cases

Abstract

The article presents clinical cases of human immunodeficiency virus (HIV) infection diagnosed in elderly patients: a man aged 70 years and a woman aged 68 years, living together for a long time. Despite approximately the same age of patients at the time of diagnosis, female patient had a more advanced clinical stage 3 of HIV infection, a more pronounced immunodeficiency (CD4+ T-lymphocytes — 285 cells/μl) compared with male patient, who had clinical stage 1 of HIV infection when diagnosing a disease with moderate immunodeficiency (CD4+ T-lymphocytes — 375 cells/μl). However, against the background of antiretroviral therapy, woman had an increase in CD4+ T-lymphocytes, she is currently in a satisfactory condition, and the life expectancy after HIV infection has been diagnosed is 7 years so far. In man, the disease was more aggressive, as the patient refused to take antiretroviral therapy, which led to the rapid progression of HIV infection, the development of acquired immune deficiency syndrome-associated tumor — Kaposi’s sarcoma, which resulted in death. Life expectancy in male patient after diagnosing HIV infection was 4 years.

Keywords

• human immunodeficiency virus infection
• acquired immune deficiency syndrome
• kaposi’s sarcoma
• mortality
• antiretroviral therapy