Communications Biology (Sep 2022)

The Musashi proteins direct post-transcriptional control of protein expression and alternate exon splicing in vertebrate photoreceptors

  • Fatimah Matalkah,
  • Bohye Jeong,
  • Macie Sheridan,
  • Eric Horstick,
  • Visvanathan Ramamurthy,
  • Peter Stoilov

DOI
https://doi.org/10.1038/s42003-022-03990-w
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 15

Abstract

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The RNA-binding proteins, Musashi 1 and 2, regulate splicing of photoreceptor-specific alternative exons and activate protein expression, and are essential for promoting translation of proteins required for vision and photoreceptor survival.