Nature Communications (Oct 2022)
Oxygen mediated oxidative couplings of flavones in alkaline water
- Xin Yang,
- Sophie Hui Min Lim,
- Jiachen Lin,
- Jie Wu,
- Haidi Tang,
- Fengyue Zhao,
- Fang Liu,
- Chenghua Sun,
- Xiangcheng Shi,
- Yulong Kuang,
- Joanne Yi Hui Toy,
- Ke Du,
- Yuannian Zhang,
- Xiang Wang,
- Mingtai Sun,
- Zhixuan Song,
- Tian Wang,
- Ji’en Wu,
- K. N. Houk,
- Dejian Huang
Affiliations
- Xin Yang
- Department of Food Science and Technology, National University of Singapore
- Sophie Hui Min Lim
- Department of Food Science and Technology, National University of Singapore
- Jiachen Lin
- Department of Food Science and Technology, National University of Singapore
- Jie Wu
- Department of Chemistry, National University of Singapore
- Haidi Tang
- Department of Chemistry, National University of Singapore
- Fengyue Zhao
- College of Sciences, Nanjing Agricultural University
- Fang Liu
- College of Sciences, Nanjing Agricultural University
- Chenghua Sun
- Department of Chemistry and Biotechnology, FSET, Swinburne University of Technology
- Xiangcheng Shi
- Department of Chemistry, National University of Singapore
- Yulong Kuang
- Department of Chemistry, National University of Singapore
- Joanne Yi Hui Toy
- Department of Food Science and Technology, National University of Singapore
- Ke Du
- Department of Food Science and Technology, National University of Singapore
- Yuannian Zhang
- Department of Food Science and Technology, National University of Singapore
- Xiang Wang
- Department of Food Science and Technology, National University of Singapore
- Mingtai Sun
- Department of Food Science and Technology, National University of Singapore
- Zhixuan Song
- Department of Food Science and Technology, National University of Singapore
- Tian Wang
- Department of Chemistry, National University of Singapore
- Ji’en Wu
- Department of Chemistry, National University of Singapore
- K. N. Houk
- Department of Chemistry and Biochemistry, University of California
- Dejian Huang
- Department of Food Science and Technology, National University of Singapore
- DOI
- https://doi.org/10.1038/s41467-022-34123-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 13
Abstract
Catalysed oxidative C-C bond formation reactions are important in the synthesis of natural products, but poorly tolerated by polyphenolic flavones. Here the authors report the reactivity of molecular oxygen in alkaline water without added catalyst for the synthesis of a collection of flavone dimers and trimers.
