Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice

S. Ya. Loginova; S. V. Borisevich; V. L. Rusinov; E. N. Ulomsky; V. N. Charushin; O. N. Chupakhin; P. V. Sorokin

Антибиотики и Химиотерапия (May 2020)

Investigation of Therapeutic Efficacy of Triazavirin Against Experimental Forest-Spring Encephalitis on Albino Mice

S. Ya. Loginova,
S. V. Borisevich,
V. L. Rusinov,
E. N. Ulomsky,
V. N. Charushin,
O. N. Chupakhin,
P. V. Sorokin

Affiliations

S. Ya. Loginova: Central Research Institute No. 48, Ministry of Defense of the Russian Federation
S. V. Borisevich: Central Research Institute No. 48, Ministry of Defense of the Russian Federation
V. L. Rusinov: Ural Federal University Named after the First President of Russia B. N. Yeltsin
E. N. Ulomsky: Ural Federal University Named after the First President of Russia B. N. Yeltsin
V. N. Charushin: Ural Federal University Named after the First President of Russia B. N. Yeltsin
O. N. Chupakhin: Ural Federal University Named after the First President of Russia B. N. Yeltsin
P. V. Sorokin: Ural Centre of Biopharmaceutical Technologies

Journal volume & issue: Vol. 60, no. 7-8
pp. 11 – 13

Abstract

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The comparative study of the therapeutic efficacy of Triazavirin against experimental Forest-Spring encephalitis on albino mice vs. the active drug Ribavirin® showed that in high doses (200-400 mg/kg) Triazavirin moderately protected the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically (p

Published in Антибиотики и Химиотерапия

ISSN: 0235-2990 (Print)
Publisher: LLC "Publishing House OKI"
Country of publisher: Russian Federation
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.antibiotics-chemotherapy.ru/

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Abstract

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