Anais Brasileiros de Dermatologia (Oct 2016)

Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient

  • Maria Carolina Prado Fleury Bariani,
  • Luiz Fernando Fróes Fleury Júnior,
  • Ana Maria Quinteiro Ribeiro,
  • Siderley de Souza Carneiro,
  • Tiago Arantes Pereira

DOI
https://doi.org/10.1590/abd1806-4841.20164401
Journal volume & issue
Vol. 91, no. 5 suppl 1
pp. 108 – 110

Abstract

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Abstract The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides lesions. However, a causal association between HHV-8 and the onset of mycosis fungoides has not been established yet. The present case reports a patient who developed Kaposi’s sarcoma lesions after a two-year UVB phototherapy to treat a mycosis fungoides. Negative immunohistochemistry staining for Kaposi’s sarcoma-associated herpesvirus in the initial mycosis fungoides lesions strengthens the absence of a link between Kaposi’s sarcoma-associated herpesvirus and mycosis fungoides. Immunosuppression caused by the lymphoma and prolonged phototherapy were probably the contribut ing factors for the onset of Kaposi’s sarcoma.

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