European Medical Journal Dermatology (May 2023)
Cutaneous Squamous Cell Carcinoma of the Hand Presenting as Clinical Perineural Invasion
Abstract
Cutaneous squamous cell carcinoma of the hand with clinical perineural invasion is uncommon. This article describes a case of a 70-year-old female who presented with a small painful nodule on the dorsum of the left hand with minor skin surface changes who underwent excisional biopsy. A deep long subcutaneous cord was palpable extending proximally from the nodule. Intraoperative findings showed a tumour growing 2.5 cm along the dorsal cutaneous nerve of the hand, and histopathological examination revealed a primary well-differentiated squamous cell carcinoma with perineural invasion. This case highlights the importance of considering malignancy as a differential diagnosis when dealing with atypical lesions.