1085 Innate immune activation by microtubule destabilizing agents enhances their efficacy in vivo, as predicted by machine learning analyses of human PBMC treated with a large, bioactive compound library

• Matthew Booty,
• Hope O’Donnell,
• Ben Komalo,
• Sarah Headland,
• Lauren Nicolaisen,
• Brandon White,
• Christian Elabd

Affiliations

Matthew Booty

SQZ Biotechnologies, Watertown, MA, USA

Hope O’Donnell

Spring Discovery, San Carlos, CA, USA

Ben Komalo

Spring Discovery, San Carlos, CA, USA

Sarah Headland

Spring Discovery, San Carlos, CA, USA

Lauren Nicolaisen

Spring Discovery, San Carlos, CA, USA

Brandon White

Spring Discovery, San Carlos, CA, USA

Christian Elabd

Spring Discovery, San Carlos, CA, USA