Nature Communications (Mar 2021)

The box C/D snoRNP assembly factor Bcd1 interacts with the histone chaperone Rtt106 and controls its transcription dependent activity

  • Benoît Bragantini,
  • Christophe Charron,
  • Maxime Bourguet,
  • Arnaud Paul,
  • Decebal Tiotiu,
  • Benjamin Rothé,
  • Hélène Marty,
  • Guillaume Terral,
  • Steve Hessmann,
  • Laurence Decourty,
  • Marie-Eve Chagot,
  • Jean-Marc Strub,
  • Séverine Massenet,
  • Edouard Bertrand,
  • Marc Quinternet,
  • Cosmin Saveanu,
  • Sarah Cianférani,
  • Stéphane Labialle,
  • Xavier Manival,
  • Bruno Charpentier

DOI
https://doi.org/10.1038/s41467-021-22077-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

Read online

Biogenesis of small nucleolar RNAs ribonucleoproteins (snoRNPs) requires dedicated assembly machinery. Here, the authors show that a subset of snoRNP assembly factors interacts, genetically or directly, with factors modulating chromatin architecture, suggesting a link between ribosome formation and chromatin functions.