Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy

Xia Gao; Xin Liao; Jing Zhang; Jinai Lin; Mei Tan

Stem Cell Research (Jan 2021)

Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy

Xia Gao,
Xin Liao,
Jing Zhang,
Jinai Lin,
Mei Tan

Affiliations

Xia Gao: Nephrology Department, Guangzhou Women and Children’s Medical Center, Guangzhou city 510623, China
Xin Liao: Nephrology Department, Guangzhou Women and Children’s Medical Center, Guangzhou city 510623, China
Jing Zhang: Ningxia Medical University, Yinchuan city 750000, China
Jinai Lin: Nephrology Department, Guangzhou Women and Children’s Medical Center, Guangzhou city 510623, China
Mei Tan: Nephrology Department, Guangzhou Women and Children’s Medical Center, Guangzhou city 510623, China

Journal volume & issue: Vol. 50
p. 102123

Abstract

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Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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