Journal of Ovarian Research (Nov 2009)

Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis

  • Manero Manuel,
  • Olartecoechea Begoña,
  • Royo Pedro,
  • Alcázar Juan

DOI
https://doi.org/10.1186/1757-2215-2-18
Journal volume & issue
Vol. 2, no. 1
p. 18

Abstract

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Abstract Objetive Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis. Patients Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain. Results From 56 patients, five cases were ultimateley excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59. Conclusion Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.