mSphere (Apr 2021)

Stability of SARS-CoV-2 Spike G614 Variant Surpasses That of the D614 Variant after Cold Storage

  • Sheng-Yu Huang,
  • Yu-An Kung,
  • Peng-Nien Huang,
  • Sheng-Yun Chang,
  • Yu-Nong Gong,
  • Yi-Ju Han,
  • Huan-Jung Chiang,
  • Kuan-Ting Liu,
  • Kuo-Ming Lee,
  • Chia-Yu Chang,
  • Chia-Ching Chang,
  • Chung-Guei Huang,
  • Shin-Ru Shih

DOI
https://doi.org/10.1128/mSphere.00104-21
Journal volume & issue
Vol. 6, no. 2

Abstract

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It has been observed that variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more stable and infectious after storage at −20°C than at 4°C. A SARS-CoV-2 S-D614G variant is currently the most dominant variant in circulation and is associated with enhanced infectivity.