Theranostics aspect of extracellular vesicle in cancer liquid biopsy

Abstract

Recent advances in cancer treatment emphasize the pivotal role of extracellular vesicles (EVs), especially exosomes (a subpopulation of EVs, originating from endosomes). Exosomes are signaling molecules in the cellular system. Its molecular signature displays the status of the cell (cell healthy or undergoing any clinical complication). Exosomes are frontiers of upcoming cancer theranostics era. This article highlighted cancer exosome complex interlink, the advantage of exosome-base liquid biopsy, the effectiveness of exosome-based cell-free therapy compared to cell therapy, complications of exosome research, and its solution. Hope, this article motivated cancer researchers to explore the exosome-based precision oncology era.

Keywords

• Extracellular vesicle
• Cancer
• Exosomes
• Cell therapy