Future Role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective

Don Husereau; Yvonne Bombard; Tracy Stockley; Michael Carter; Scott Davey; Diana Lemaire; Erik Nohr; Paul Park; Alan Spatz; Christine Williams; Aaron Pollett; Bryan Lo; Stephen Yip; Soufiane El Hallani; Harriet Feilotter

doi:10.3390/curroncol30110700

Current Oncology (Oct 2023)

Future Role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective

Don Husereau,
Yvonne Bombard,
Tracy Stockley,
Michael Carter,
Scott Davey,
Diana Lemaire,
Erik Nohr,
Paul Park,
Alan Spatz,
Christine Williams,
Aaron Pollett,
Bryan Lo,
Stephen Yip,
Soufiane El Hallani,
Harriet Feilotter

Affiliations

Don Husereau: School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1G 5Z3, Canada
Yvonne Bombard: Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON M5T 3M6, Canada
Tracy Stockley: Division of Clinical Laboratory Genetics, Laboratory Medicine Program, University Health Network, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada
Michael Carter: Department of Pathology and Laboratory Medicine, Nova Scotia Health (Central Zone), Halifax, NS B3H 1V8, Canada
Scott Davey: Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON K7L 3N6, Canada
Diana Lemaire: Ontario Institute for Cancer Research, 661 University Ave, Toronto, ON M5G 0A3, Canada
Erik Nohr: Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada
Paul Park: Department of Pathology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3A 1R9, Canada
Alan Spatz: Division of Pathology, McGill University Health Center, 1001 Decarie Blvd., Montreal, QC H4A 3J, Canada
Christine Williams: Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON K7L 3N6, Canada
Aaron Pollett: Pathology & Laboratory Medicine, Sinai Health System, Toronto, ON M5G 1X5, Canada
Bryan Lo: The Ottawa General Hospital, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada
Stephen Yip: Department of Pathology & Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z7, Canada
Soufiane El Hallani: Alberta Precision Laboratory, Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2R7, Canada
Harriet Feilotter: Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON K7L 3N6, Canada

DOI: https://doi.org/10.3390/curroncol30110700
Journal volume & issue: Vol. 30, no. 11
pp. 9660 – 9669

Abstract

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Genome-based testing in oncology is a rapidly expanding area of health care that is the basis of the emerging area of precision medicine. The efficient and considered adoption of novel genomic medicine testing is hampered in Canada by the fragmented nature of health care oversight as well as by lack of clear and transparent processes to support rapid evaluation, assessment, and implementation of genomic tests. This article provides an overview of some key barriers and proposes approaches to addressing these challenges as a potential pathway to developing a national approach to genomic medicine in oncology.

Published in Current Oncology

ISSN: 1198-0052 (Print); 1718-7729 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.mdpi.com/journal/curroncol

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