Nature Communications (Apr 2021)

Real-world stress resilience is associated with the responsivity of the locus coeruleus

  • Marcus Grueschow,
  • Nico Stenz,
  • Hanna Thörn,
  • Ulrike Ehlert,
  • Jan Breckwoldt,
  • Monika Brodmann Maeder,
  • Aristomenis K. Exadaktylos,
  • Roland Bingisser,
  • Christian C. Ruff,
  • Birgit Kleim

DOI
https://doi.org/10.1038/s41467-021-22509-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

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Individuals vary considerably in how they are affected by stress. Here, the authors show that the severity of psychopathological symptoms triggered by prolonged real-life stress relate to fMRI-measured responsivity of the human brainstem arousal system and associated pupil responses.