Genetic polymorphisms associated with the development of arrhythmic type of cardiovascular events

Abstract

The review analyzes the global agenda on mutational status of genes associated with adverse cardiovascular events of arrhythmic type. Whole exome sequencing will identify a risk group for the likelihood of early or delayed cardiovascular events of arrhythmic type, especially among patients receiving anticancer therapy with cardiotoxic drugs. The dedicated up-to-date panel of genetic polymorphisms will provide an opportunity to optimize management of patients, based on not only clinical, paraclinical and anamnestic data.

Keywords

• genetic polymorphisms
• cardiotoxicity
• oncohematology
• arrhythmias
• genetics