ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells

Abstract

The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.