Nature Communications (Jul 2021)

Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

  • Gabriela Alvarado,
  • Wilhelm Salmen,
  • Khalil Ettayebi,
  • Liya Hu,
  • Banumathi Sankaran,
  • Mary K. Estes,
  • B. V. Venkataram Prasad,
  • James E. Crowe

DOI
https://doi.org/10.1038/s41467-021-24649-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

Read online

Noroviruses can cause gastroenteritis and there is currently no licensed vaccine or specific treatment available. Here, the authors isolate human monoclonal antibodies and characterize one antibody (NORO-320) with broad reactivity to genogroup I and II noroviruses.