Determination of mefenamic acid in aqueous solutions using merging zone – continuous flow injection

Abstract

This research aims at using a novel algorithm to determine the concentration of mefenamic acid (MA) in solutions using merging zone-continuous flow injection. The MA concentration in aqueous solutions was determined using this technology, and the results obtained using this method were compared to those obtained using more conventional methods. All flow injection analyses were carried out utilizing a Rheodyne valve 7725, a Rabbit peristaltic pump, a BioLogic QuadTec UV-Vis Detector, and a Sartorius CPA2P Competence Analytical Balance, as well as a Sartorius CPA2P Competence Analytical Balance. The data is then received by a signal detector and a specialized software spectrometer. A spectroscopic scan is used to determine the maximum wavelength of the product, a calibration curve is created, and measurements are taken to estimate the drug's absolute concentrations in aqueous solutions. The detection and quantitative limits were set to 0.021 and 0.071 parts per million. This treatment is popular and could be a good alternative to conventional methods because it is simple, rapid, precise, inexpensive, and adaptable. HIGHLIGHTS A novel merging zone-continuous flow injection was used to measure the mefenamic acid in solutions.; The obtained detection and quantitative limits were set to 0.021 and 0.071 parts per million.; This method could be a good alternative to the conventional methods because it is simple, rapid, precise, inexpensive, and adaptable.;

Keywords

• flow injection analyses
• mefenamic acid
• version 15 of the g-chrom software
• zone of consolidation