The fragmentary literature data on Apiaceae seed antioxidant potential elicited a comparative evaluation work of seed biochemical profile between 11 species and 43 cultivars grown in similar conditions: anise, lovage, fennel, coriander, caraway, parsley, celery, dill, carrot, parsnip and chervil. Among the different solvents, temperature and duration regimes applied, 70% EtOH, 80 °C and 1 h running showed the best extraction efficiency of antioxidants. Total antioxidant activity (AOA) decreased as follows: lovage > anise > parsley > celery > fennel = dill > coriander > caraway > parsnip > carrot > chervil. Lovage, anise and fennel demonstrated the highest levels of total phenolics (TP), AOA and potassium. A positive correlation was recorded between total dissolved solids (TDS) and K and between AOA and TP content (r = 0.86 and r = 0.79 respectively, at p p < 0.05).