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Encephalitis associated with COVID-19 in a 13-year-old girl: A case report

Medwave. 2020;20(07) DOI 10.5867/medwave.2020.07.7984


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Journal Title: Medwave

ISSN: 0717-6384 (Online)

Publisher: Medwave Estudios Limitada

LCC Subject Category: Medicine: Medicine (General)

Country of publisher: Chile

Language of fulltext: English, Spanish

Full-text formats available: PDF, HTML



Nadin Melina Conto-Palomino (Servicio de Pediatría, Hospital Nacional Arzobispo Loayza, Lima, Perú)

María Luz Cabrera-Bueno (Servicio de Pediatría, Hospital Nacional Arzobispo Loayza, Lima, Perú)

Kenneth Grenis Vargas-Ponce (Servicio de Neumología, Hospital Nacional Dos de Mayo, Lima, Perú)

Evelina Andrea Rondón-Abuhadba (Escuela Profesional de Medicina Humana, Facultad de Ciencias de la Salud, Universidad Nacional de San Antonio Abad del Cusco, Cusco, Perú)

Noé Atamari-Anahui (Universidad San Ignacio de Loyola, Vicerrectorado de Investigación, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Perú)


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Time From Submission to Publication: 12 weeks


Abstract | Full Text

There are limited reports of neurological symptoms in the pediatric population with COVID-19. We report a 13-year-old girl with three days of illness characterized by headache, non-explosive vomiting, fever, and sudden-onset sensory disorder associated with difficulty in standing and hemiparesis in limbs without evidence of meningeal signs. Brain tomography revealed diffuse brain edema, and the cerebrospinal fluid study was consistent with a viral infection. COVID-19 was diagnosed based on serology. The patient had an untoward clinical course despite treatment with hydroxychloroquine, azithromycin, and corticosteroids, dying on the third day of hospitalization. Encephalitis in a patient with COVID-19 is not frequently reported in the pediatric population. It should be considered in the differential diagnosis in patients who arrives at the emergency with a sensory disorder or neurological symptomatology in the context of the COVID-19 pandemic.