Benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine: A New Fluorescent Probe for the High-Sensitivity and Real-Time Visual Monitoring of Phosgene
Yingzhen Zhang,
Jun Xiao,
Ruiying Peng,
Xueliang Feng,
Haimei Mao,
Kunming Liu,
Zhenzhong Liu,
Chunxin Ma
Affiliations
Yingzhen Zhang
School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, China
Jun Xiao
School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, China
Ruiying Peng
School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, China
Xueliang Feng
State Key Laboratory of Marine Resource Utilization in South China Sea, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China
Haimei Mao
Key Laboratory of Quality Safe Evaluation and Research of Degradable Material, State Administration for Market Regulation, Hainan Academy of Inspection and Testing, Haikou 570203, China
Kunming Liu
School of Chemistry and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou 341000, China
Zhenzhong Liu
Taizhou Key Laboratory of Medical Devices and Advanced Materials, Taizhou Institute of Zhejiang University, Taizhou 318000, China
Chunxin Ma
State Key Laboratory of Marine Resource Utilization in South China Sea, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China
The detection of highly toxic chemicals such as phosgene is crucial for addressing the severe threats to human health and public safety posed by terrorist attacks and industrial mishaps. However, timely and precise monitoring of phosgene at a low cost remains a significant challenge. This work is the first to report a novel fluorescent system based on the Intramolecular Charge Transfer (ICT) effect, which can rapidly detect phosgene in both solution and gas phases with high sensitivity by integrating a benzo[1,2-b:6,5-b’]dithiophene-4,5-diamine (BDTA) probe. Among existing detecting methods, this fluorescent system stands out as it can respond to phosgene within a mere 30 s and has a detection limit as low as 0.16 μM in solution. Furthermore, the sensing mechanism was rigorously validated through high-resolution mass spectrometry (HRMS) and density functional theory (DFT) calculations. As a result, this fluorescent probing system for phosgene can be effectively adapted for real-time, high-sensitivity sensing and used as a test strip for visual monitoring without the need for specific equipment, which will also provide a new strategy for the fluorescent detection of other toxic materials.
