Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients

• Mayumi Hangai,
• Takahisa Kawaguchi,
• Masatoshi Takagi,
• Keitaro Matsuo,
• Soyoung Jeon,
• Charleston W.K. Chiang,
• Andrew T. Dewan,
• Adam J. de Smith,
• Toshihiko Imamura,
• Yasuhiro Okamoto,
• Akiko M. Saito,
• Takao Deguchi,
• Michiaki Kubo,
• Yoichi Tanaka,
• Yoko Ayukawa,
• Toshinari Hori,
• Kentaro Ohki,
• Nobutaka Kiyokawa,
• Takeshi Inukai,
• Yuki Arakawa,
• Makiko Mori,
• Daisuke Hasegawa,
• Daisuke Tomizawa,
• Hiroko Fukushima,
• Yuki Yuza,
• Yasushi Noguchi,
• Yuichi Taneyama,
• Setsuo Ota,
• Hiroaki Goto,
• Masakatsu Yanagimachi,
• Dai Keino,
• Kazutoshi Koike,
• Daisuke Toyama,
• Yozo Nakazawa,
• Kozue Nakamura,
• Koichi Moriwaki,
• Yujin Sekinaka,
• Daisuke Morita,
• Shinsuke Hirabayashi,
• Yosuke Hosoya,
• Yuri Yoshimoto,
• Hiroki Yoshihara,
• Miwa Ozawa,
• Shinobu Kobayashi,
• Naho Morisaki,
• Tshewang Gyeltshen,
• Osamu Takahashi,
• Yukinori Okada,
• Makiko Matsuda,
• Toshihiro Tanaka,
• Johji Inazawa,
• Junko Takita,
• Yasushi Ishida,
• Akira Ohara,
• Catherine Metayer,
• Joseph L. Wiemels,
• Xiaomei Ma,
• Shuki Mizutani,
• Katsuyoshi Koh,
• Yukihide Momozawa,
• Keizo Horibe,
• Fumihiko Matsuda,
• Motohiro Kato,
• Atsushi Manabe,
• Kevin Y. Urayama

Affiliations

Mayumi Hangai

Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatrics, The University of Tokyo, Tokyo

Takahisa Kawaguchi

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto

Masatoshi Takagi

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo

Keitaro Matsuo

Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya

Soyoung Jeon

Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles

Charleston W.K. Chiang

Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles

Andrew T. Dewan

Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven

Adam J. de Smith

Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles

Toshihiko Imamura

Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto

Yasuhiro Okamoto

Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima

Akiko M. Saito

Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya

Takao Deguchi

Children's Cancer Center, National Center for Child Health and Development, Tokyo

Michiaki Kubo

Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Kanagawa

Yoichi Tanaka

Division of Medicinal Safety Science, National Institute of Health Sciences, Kawasaki

Yoko Ayukawa

Department of Social Medicine, National Center for Child Health and Development, Tokyo

Toshinari Hori

Department of Pediatrics, Aichi Medical University Hospital, Nagoya

Kentaro Ohki

Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo

Nobutaka Kiyokawa

Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo

Takeshi Inukai

Department of Pediatrics, University of Yamanashi, Yamanashi

Yuki Arakawa

Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama

Makiko Mori

Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama

Daisuke Hasegawa

Department of Pediatrics, St. Luke’s International Hospital, Tokyo

Daisuke Tomizawa

Children's Cancer Center, National Center for Child Health and Development, Tokyo

Hiroko Fukushima

Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba

Yuki Yuza

Department of Hematology/Oncology, Tokyo Metropolitan Children’s Medical Center, Tokyo

Yasushi Noguchi

Department of Pediatrics, Japanese Red Cross Narita Hospital, Chiba

Yuichi Taneyama

Department of Hematology/Oncology, Chiba Children’s Hospital, Chiba

Setsuo Ota

Department of Pediatrics, Teikyo University Chiba Medical Center, Chiba

Hiroaki Goto

Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama

Masakatsu Yanagimachi

Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama

Dai Keino

Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama

Kazutoshi Koike

Division of Pediatric Hematology and Oncology, Ibaraki Children's Hospital, Mito

Daisuke Toyama

Division of Pediatrics, Showa University Fujigaoka Hospital, Yokohama

Yozo Nakazawa

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto

Kozue Nakamura

Department of Pediatrics, Teikyo University Hospital, Tokyo

Koichi Moriwaki

Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Saitama

Yujin Sekinaka

Department of Pediatrics, National Defense Medical College, Saitama

Daisuke Morita

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto

Shinsuke Hirabayashi

Department of Pediatrics, Hokkaido University, Sapporo

Yosuke Hosoya

Department of Pediatrics, St. Luke’s International Hospital, Tokyo

Yuri Yoshimoto

Department of Pediatrics, National Center for Global Health and Medicine, Tokyo

Hiroki Yoshihara

Department of Pediatrics, St. Luke’s International Hospital, Tokyo

Miwa Ozawa

Department of Pediatrics, St. Luke’s International Hospital, Tokyo

Shinobu Kobayashi

Department of Social Medicine, National Center for Child Health and Development, Tokyo

Naho Morisaki

Department of Social Medicine, National Center for Child Health and Development, Tokyo

Tshewang Gyeltshen

Graduate School of Public Health, St. Luke's International University, Tokyo

Osamu Takahashi

Graduate School of Public Health, St. Luke's International University, Tokyo

Yukinori Okada

Department of Statistical Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Kanagawa

Makiko Matsuda

Department of Human Genetics and Disease Diversity, Tokyo Medical Dental University, Tokyo

Toshihiro Tanaka

Department of Human Genetics and Disease Diversity, Tokyo Medical Dental University, Tokyo

Johji Inazawa

Department of Molecular Cytogenetics, Tokyo Medical and Dental University, Tokyo

Junko Takita

Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto

Yasushi Ishida

Pediatric Medical Center, Ehime Prefectural Central Hospital, Matsuyama

Akira Ohara

Department of Pediatrics, Toho University, Tokyo

Catherine Metayer

School of Public Health, University of California Berkeley, Berkeley, California

Joseph L. Wiemels

Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles

Xiaomei Ma

Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven

Shuki Mizutani

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo

Katsuyoshi Koh

Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama

Yukihide Momozawa

Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Kanagawa

Keizo Horibe

Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya

Fumihiko Matsuda

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto

Motohiro Kato

Department of Pediatrics, The University of Tokyo, Tokyo

Atsushi Manabe

Department of Pediatrics, Hokkaido University, Sapporo

Kevin Y. Urayama

Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan; Graduate School of Public Health, St. Luke's International University, Tokyo