Current Issues in Pharmacy and Medical Sciences (Jun 2021)

Neurological manifestation of cancer – paraneoplastic syndromes

  • Szklener Katarzyna,
  • Mandziuk Slawomir

DOI
https://doi.org/10.2478/cipms-2021-0018
Journal volume & issue
Vol. 34, no. 2
pp. 74 – 76

Abstract

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Neurological paraneoplastic syndromes (NPS) belong to a heterogeneous group of disorders affecting the nervous system. NPS occur as a result of immunological reaction to the tumor. As a result, the isolated syndrome is formed and manifests itself in many different ways, for example: limbic encephalitis, ataxia, dominant cerebellar degeneration, psychiatric disturbances, myasthenia gravis or diffuse encephalomyelitis. Detection of NPS is solely based on the presence of specific anti-neural antibodies. Although NPS had been previously considered unresponsive to therapy, some research has shown that there are effective therapies, including cancer- and immunotherapy targeted therapies.

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