CYTOLOGICAL ASSESSMENT OF HEALING ODONTOGENIC INFLAMMATORY PROCESSES WHEN APPLYING HYDROGELS

Abstract

INTRODUCTION: Odontogenic inflammatory processes constitute a significant part among maxillofacial disorders, as well as among all inflammatory processes in organism. The author used hydrogels saturated with silver ions and an antioxidant drug for local treatment of odontogenic abscesses and phlegmons. AIM OF THE STUDY. To conduct cytological assessment when applying hydrogels saturated with silver ions and an antioxidant drug for local treatment of odontogenic abscesses and phlegmons. STUDY SUBJECT AND STUDY METHODS. 50 patients with odontogenic abscesses and phlegmons of maxillofacial area had been examined. To study the dynamics of the inflammatory process, cytology was performed on days 1, 3, 5, 7, 10. STUDY RESULTS AND THEIR DISCUSSION. No differences were found in both groups of patients on the first day of treatment. On the second or third day, there was a higher number of red blood cells and a significant decrease in the number of neutrophilic granulocytes in the study group than in the comparator group. In the fibrin strands, accumulation of single macrophages, histiocytes, fibrocytes and monocytes were noted. During analysis of cytograms, an increase in the number of erythrocytes, histiocytes, fibroblasts, almost complete absence of neutrophilic granulocytes and single macrophages in the main group were observed on the 4-5 day, indicating the formation of granulation tissue and accelerated onset of proliferation. On the sixth day, patients of the study group had almost no neutrophils and no signs of inflammation, unlike patients in comparator group. CONCLUSIONS. Cytology results has shown that application of hydrogels saturated with silver ions and an antioxidant drug for local treatment of odontogenic abscesses and phlegmons accelerates the healing time of postoperative wounds.

Keywords

• wounds healing
• cytology
• hydrogels
• odontogenic abscesses and phlegmons